I first turned off the Anti-Virus option in McAfee and then updated to version 2.50.5 again.
Installation went well but still had no audio. Anti-virus remained off.
I excluded JTAlertV2.Manager.exe from McAfee scans and turned Anti-Virus back on.
I now have sound again. Test Sound Output working OK now.
I guess that was the problem.
73 de Walt, W6SA